Acupuncture May Prevent Some
Cases of Chemotherapy-Induced Nausea and Vomiting
CancerConsultants
October 04, 2005
According to a review published in the Journal of
Clinical Oncology, certain types of
acupuncture-point stimulation may relieve
chemotherapy-induced nausea or vomiting, but few
well-designed studies have been conducted.
Chemotherapy is often difficult for
cancer patients due to severe nausea and vomiting.
Despite significant progress over the past decade in
controlling chemotherapy-induced nausea and vomiting
(CINV), more than half of all patients receiving
chemotherapy still suffer from these side effects.
Furthermore, nausea may persist when vomiting is
controlled. These symptoms can be severely
debilitating and often lead patients to refuse
further courses of chemotherapy. This minimizes
chances for an optimal outcome. CINV can either be
acute (occurring within the first 24 hours after
chemotherapy), delayed (occurring more than 24 hours
after chemotherapy), or both. Delayed nausea and
vomiting is more common than acute nausea and
vomiting.
CINV can often be controlled through the
use of antiemetic medications, but there is also
interest in exploring alternative therapies such as
acupuncture. The acupuncture point thought to be
associated with relief of nausea is P6, which is
located on the wrist. This point can be stimulated
through a variety of methods, including manual
acupuncture (insertion of needles),
electroacupuncture (passing electric current through
the inserted needle), noninvasive electrostimulation
(application of electric current without a needle),
or acupressure (pressure applied by the fingers or
an elastic wristband).
In order to summarize what is known
about the effects of these methods on relief of CINV,
researchers combined data from 11 published clinical
trials. These studies involved a total of 1,247
patients and used a variety of methods for
acupuncture-point stimulation. For all methods
combined, there was some evidence of a reduced risk
of acute vomiting. Specific methods performed as
follows:
- Electroacupuncture appeared to have the
greatest effect on vomiting.
- Acupressure appeared to have the greatest
effect on nausea.
- Noninvasive electrostimulation did not
appear to provide a benefit.
Although this review describes possible
benefits of acupuncture-point stimulation for CINV,
it’s still unclear whether these methods will
improve outcomes among patients who are treated with
current antiemetic medications. There’s also little
information available about the use of
acupuncture-point stimulation for delayed CINV.
Fortunately, an increasing number of well-designed
studies are focusing on complementary and
alternative therapies. More thorough information
about the role of acupuncture in the prevention of
CINV and other symptoms should be forthcoming.
Reference: Ezzo J,
Vickers A, Richardson MA et al. Acupuncture-point
stimulation for chemotherapy-induced nausea and
vomiting. Journal of Clinical Oncology .
2005;23:7188-7198.
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